The Advanced Microsphere-Based Wound Healing Technology 

Basic wound healing is a complex biological process that requires the orchestrated sequence of multiple cellular and biochemical processes.
During normal healing and wound closure, cells proliferate and divide, releasing growth factors. New blood vessels are created, a collagen matrix is formed, and remodeling occurs.
There are basically 3 phases in the wound healing process: the Inflammatory Phase, the Proliferative Phase and the Remodeling Phase.
In patients suffering from chronic wounds this tissue repair mechanism is deregulated, degenerated or impaired and quite often results in a very slow or even arrested healing.  

Wound Healing Therapeutic Concept

Polyheal's wound healing technology is based on the concept of triggering the patient's own cells to regenerate the deteriorated tissue of chronic wounds. This process of tissue repair is the core of Polyheal's wound healing technology. The specially designed physical-chemical features of the microspheres were designed to optimize the therapeutic process.

The proprietary tissue repair technology is based on the use of non-biodegradable, chemically inert synthetic charged microspheres, characterized by their narrow size distribution. 

The Company’s first product, consists of  a water based suspension of microspheres, which can be easily applied onto the acute or chronic wound by direct wetting or by spraying. Polyheal’s findings show that its charged microspheres have a therapeutic effect on wound healing, by their activation of different types of cells in the wound space (inflammatory cells, fibroblasts and keratinocytes).  

The company's advanced chronic wound care and tissue repair product has been successfully tested in clinical trials for promoting the initiation of granulation tissue growth and remodeling of damaged skin tissue, when applied to the wound surface. 
 

Our primary focus is clinical availability of advanced tissue repair treatments that bring improvements to health and quality of life for chronic wounds patients worldwide.

Polyheal collaborates with wound care specialists to develop innovative wound healing products with state-of-the-art clinical evidence and to support chronic wound patients with professional treatment guidelines.